Quantum Regenerative and Biomedical Engineering Team

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Publications

Original Papers

2024

  1. Shimada T., Ueda Y., Takemaru H., Baba Y., Yukawa H. Nano-quantum sensors-based imaging and sensing for target-based drug discovery and development, Trends Analyt. Chem. 2024; 171: 117496.
    2. DOI: 10.1016/j.trac.2023.117496
  2. Yamada S., Yamada K., Sugawara A., Baba Y., Yukawa H. Near-infrared-II fluorescence/magnetic resonance double modal imaging of transplanted stem cells using lanthanide co-doped gadolinium oxide nanoparticles, Anal. Sci. 2024; 40: 1043-1050. Hot Article in 2024
    3. DOI: 10.1007/s44211-024-00507-9
  3. Takahashi T., Zhang H., Agetsuma M., Nabekura J., Otomo K., Okamura Y., Nemoto T. Large-scale cranial window for in vivo mouse brain imaging utilizing fluoropolymer nanosheet and light-curable resin, Commun. Biol. 2024; 7: 212.
    4. DOI: 10.1038/s42003-024-05865-8
  4. Rikiyama K., Maehara N., Abe H., Nishimura Y., Yukawa H., Kaminaga K., Igarashi R., Osada K. Quantification of Poly(ethylene glycol) Crowding on Nanodiamonds toward Quantum Biosensor for Improved Prevention Effects on Protein Adsorption and Lung Accumulation, Langmuir 2024; 40(18): 9471–9480.
    5. DOI: 10.1021/acs.langmuir.3c03988
  5. Iwatake M., Nagamura-Inoue T., Doi R., Tanoue Y., Ishii M., Yukawa H., Tsuchiya T. Designer umbilical cord-stem cells induce alveolar wall regeneration in pulmonary disease models, Front. Immunol. 2024; 15: 1384718.
    6. DOI: 10.3389/fimmu.2024.1384718
  6. Miki K., Oe M., Suzuki K., Miki K., Mu H., Kato Y., Iwatake M., Yukawa H., Baba Y., Ueda Y., Mori Y., Ohe K. Dual-Responsive Near-Infrared Turn-On Fluorescent Probe for Cancer Stem Cell-Specific Visualization, J. Mater. Chem. B 2024; 12: 6959-6967.
    7. DOI: 10.1039/d4tb00897a
  7. Shimada T., Ueda Y., Baba Y., Yukawa H. Advances of Fluorescent Nanodiamond Platforms for Intracellular and On-Chip Biosensing, Biosensors 2024; 14(7): 340.
    8. DOI: 10.3390/bios14070340
  8. Iwatake M., Morita S., Takahashi K., Sato K., Miyagi-Shiohira C., Noguchi H., Baba Y., Yukawa H. Establishment of a stem cell administration imaging method in bleomycin-induced pulmonary fibrosis mouse models, Sci. Rep. 2024; 14: 18905.
    9. DOI: 10.1038/s41598-024-67586-6
  9. Onoshima D., Uchida K., Iida T., Kojima T., Ikeda Y., Iwata D., Nagasawa I., Yukawa H., Baba Y. Single-cell detection and linear discriminant analysis of bacterial Raman spectra in glass filter microholes, Anal. Methods 2024; 16(39): 6746-6750.
    10. DOI: 10.1039/d4ay01272k
  10. Yasui T., Natsume A., Yanagida T., Nagashima K., Washio T., Ichikawa Y., Chattrairat K., Naganawa T., Iida M., Kitano Y., Aoki K., Mizunuma M., Shimada T., Takayama K., Ochiya T., Kawai T., Baba Y. Early Cancer Detection via Multi-microRNA Profiling of Urinary Exosomes Captured by Nanowires, Anal. Chem. 2024 in press.
    11. DOI: 10.1021/acs.analchem.4c02488
  11. Yukawa H., Kono H., Ishiwata H., Igarashi R., Takakusagi Y., Arai S., Hirano Y., Suhara T., Baba Y. Biological Nano Quantum Sensors, Quantum Technology-Based Hyperpolarized MRI/NMR, Quantum Biology, and Quantum Biotechnology, Chem. Soc. Rev. 2024 in press.
  12. Asano T., Suga H., Niioka H., Yukawa H., Sakakibara M., Taga S., Soen M., Miwata T., Sasaki H., Seki T., Hasegawa S., Murakami S., Abe M., Yasuda Y., Miyata T., Kobayashi T., Sugiyama M., Onoue T., Hagiwara D., Iwama S., Baba Y., Iwama S. A deep learning approach to predict differentiation outcomes in hypothalamic pituitary organoids, Commun. Biol. 2024 in press.
  13. Ueda Y., Tsukahara K., Hasumi M., Uyama K., Yukawa H., Kato T., Toda T., Ohta S., Nishii K. Cis-1,4-specific polymerization of 1,3-conjugated dienes with bis (benzimidazole) NiCl2 catalyst system, Polymer 2024 in press.

2023

  1. Shimada T., Takeshita D., Ito S., Yasui T., Baba Y. MicroRNA Extraction from Extracellular Vesicles in Body Fluids Using PMMA-based Nnowire Devices, BUNSEKI KAGAKU 2023; 72: 105-110.
    2. DOI: 10.2116/bunsekikagaku.72.105
  2. Chattrairat K., Yasui T., Suzuki S., Natsume A., Nagashima K., Iida M., Zhang M., Shimada T., Kato A., Aoki K., Ohka F., Yamazaki S., Yanagida T., Baba Y. All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model, ACS nano. 2023; 17(3): 2235-2244.
    3. DOI: 10.1021/acsnano.2c08526
  3. Carrillo-Reid L., Agetsuma M., Kropff E. Editorial: Reconfiguration of Neuronal Ensembles Throughout Learning, Front. Syst. Neurosci. 2023; 17: 1161967.
    4. DOI: 10.3389/fnsys.2023.1161967
  4. Onoshima D., Sato R., Yukawa H., Nohira K., Min H., Baba Y. Development of Sampling and Measurement Technology for Indoor Particulate Matter Using a Small Drone, Earozoru Kenkyu 2023; 38(1): 30-32.
    5. DOI: 10.11203/jar.38.30
  5. Yamada S., Yukawa H., Oshizumi Y., Kitamura K., Mizumaki T., Oohara T., Nanizawa E., Hirano F., Sato K., Ishikawa T., Baba Y. In Vivo Real-Time Quantum Dots Imaging to Track Transplanted Adipose Stem Cells in Different Inflammatory States of Acute Liver Failure Mice, Cell Transplant. 2023; 32: 1-11.
    6. DOI: 10.1177/09636897231176442
  6. Hasegawa K., Raudales J. L. M., Takashi I., Yoshida T., Honma R., Iwatake M., Tran S., Seki M., Asahina I., Sumita Y. Effective-mononuclear cell (E-MNC) therapy alleviates salivary gland damage by suppressing lymphocyte infiltration in Sjögren-like disease, Front. Bioeng. Biotechnol. 2023; 11: 1144624.
    7. DOI: 10.3389/fbioe.2023.1144624
  7. Yukawa H., Sato K., Baba Y. Theranostics applications of quantum dots in regenerative medicine, cancer medicine, and infectious diseases, Adv. Drug. Deliv. Rev. 2023; 200: 114863. Front Cover
    8. DOI: 10.1016/j.addr.2023.114863
  8. Takahashi H., Yasui T., Hirano M., Shinjo K., Miyazaki Y., Shinoda W., Hasegawa T., Natsume A., Kitano Y., Ida M., Zhang M., Shimada T., Paisrisarn P., Zhu Z., Ohka F., Aoki K., Rahong S., Nagashima K., Yanagida T., Baba Y. Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy, Biosens. Bioelectron. 2023; 234: 115318-115318.
    9. DOI: 10.1016/j.bios.2023.115318
  9. Hisanaga M., Tsuchiya T., Watanabe H., Shimoyama K., Iwatake M., Tanoue Y., Maruyama K., Yukawa H., Sato K., Kato Y., Matsumoto K., Miyazaki T., Doi R., Tomoshige K., Nagayasu T. Adipose-Derived Mesenchymal Stem Cells Attenuate Immune Reactions Against Pig Decellularized Bronchi Engrafted into Rat Tracheal Defects, Organogenesis 2023; 19(1): 2212582.
    10. DOI: 10.1080/15476278.2023.2212582
  10. Honma R., Takashi I., Seki M., Iwatake M., Ogaeri T., Hasegawa K., Ohba S., Tran S., Asahina I., Sumita Y. Immunomodulatory Macrophages Enable E-MNC Therapy for Radiation-Induced Salivary Gland Hypofunction, Cells 2023; 12(10): 1417.
    11. DOI: 10.3390/cells12101417
  11. Mizoguchi S., Tsuchiya T., Doi R., Obata T., Iwatake M., Matsumoto H., Yukawa H., Hayashi H., Li T.S., Yamamoto K., Matsumoto K., Miyazaki T., Tomoshige K., Nagayasu T. A novel ex vivo lung cancer model based on bioengineered rat lungs, Front. Bioeng. Biotechnol. 2023; 11: 1179830.
    12. DOI: 10.3389/fbioe.2023.1179830
  12. Yokoi A., Ukai M., Yasui T, Inokuma Y., Hyeon-Deuk K., Matsuzaki J., Yoshida K., Kitagawa M., Chattrairat K., Iida M., Shimada T., Manabe Y., Chang I, Asano-Inami E., Koya Y., Nawa A., Nakamura K., Kiyono T., Kato T., Hirakawa A., Yoshioka Y., Ochiya T., Hasegawa T., Baba Y., Yamamoto Y., Kajiyama H. Identifying high-grade serous ovarian carcinoma-specific extracellular vesicles by polyketone-coated nanowires, Sci. Adv. 2023; 9(27): eade6958.
    13. DOI: 10.1126/sciadv.ade6958
  13. Kishimoto T., Agetsuma M., Hoshino A., Takahashi H. Needle‐type pressure sensor with silicone oil and parylene membrane inside for minimally invasive measurement, Elec. Commun. Jap. 2023; 106(3): E12420.
    14. DOI: 10.1002/ecj.12420
  14. Matsuoka K., Yamada M., Fukatsu N., Goto K., Shimizu M., Kato A., Kato Y., Yukawa Y., Baba Y., Sato M., Sato K. Contrast-enhanced ultrasound imaging for monitoring the efficacy of near-infrared photoimmunotherapy, eBioMedicine 2023; 95: 104737.
    15. DOI: 10.1016/j.ebiom.2023.104737
  15. Agetsuma M., Sato I., Tanaka Y., Carrillo-Reid L., Kasai A., Noritake A., Arai Y., Yoshitomo M., Inagaki T., Yukawa H., Hashimoto H., Nabekura J., Nagai T. Activity-dependent organization of prefrontal hub-networks for associative learning and signal transformation, Nat. Commun. 2023; 14(1): 5996.
    16. DOI: 10.1038/s41467-023-41547-5
  16. Tanoue Y., Tsuchiya T., Miyazaki T., Iwatake M., Watanabe H., Yukawa H., Sato K., Hatachi G., Shimoyama K., Matsumoto K., Doi R., Tomoshige K., Nagayasu T. Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model, Cell Transplant. 2023; 32.
    17. DOI: 10.1177/09636897231207177
  17. Shimada T., Fujino K., Yasui T., Kaji N., Ueda Y., Fujii K., Yukawa H., Baba Y. Resistive pulse sensing on a capillary-assisted microfluidic plat-form for on-site single particle analyses, Anal. Chem. 2023; 95(50): 18335-18343.
    18. DOI: 10.1021/acs.analchem.3c02539

2022

  1. Minchuan L., Yukawa H., Baba Y. Micro/Nano-fluidic devices and in vivo fluorescence imaging based on quantum dots for cytologic diagnosis, Lab Chip 2022; 22, 2223-2236. Front Cover
  2. Oshimi K., Nishimura Y., Matsubara T., Tanaka M., Shikoh E., Zhao L., Zou Y., Komatsu N., Ikado Y., Takezawa Y., Kage-Nakadai E., Izutsu Y., Yoshizato K., Morita S., Tokunaga M., Yukawa H., Baba Y., Teki Y., Fujiwara M. Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples, Lab Chip 2022; 22: 2519-2530. Back Cover, Hot Article in 2022
  3. Minchuan L., Yukawa H., Baba Y. Fluorescent/magnetic nano-aggregation via electrostatic force between modified quantum dot and iron oxide nanoparticles for bimodal imaging of U87MG tumor cells, Anal. Sci. 2022; 38: 1141-1147. Front Cover, Hot Article in 2022
  4. Minchuan L., Yukawa H., Sato, K., Tozawa, M., Tokunaga, M., Kameyama, T., Torimoto, T., Baba, Y. Multifunctional Magnetic CuS/Gd2O3 Nanoparticles for Fluorescence/MR Bimodal Imaging-guided Photothermal-intensified Chemodynamic Synergetic Therapy of Targeted Tumors, ACS Appl. Mater. Interfaces 2022; 14(30): 34365–34376.
  5. Yamada S., Yukawa H., Yamada K., Murata Y., Jo J., Yamamoto M., Sugawara-Narutaki A., Tabata Y., Baba Y. In vivo multimodal imaging of stem cells using nanohybrid particles incorporating quantum dots and magnetic nanoparticles, Sensors 2022; 22(15): 5705.
  6. Takahashi K., Yasui H., Taki S., Shimizu M., Koike C., Taki K., Yukawa H., Baba Y., Kobayashi H., Sato K. Near-infrared-induced drug release from antibody–drug double conjugates exerts a cytotoxic photo-bystander effect, Bioeng. Transl. Med. 2022; 7(3): e10388.
  7. Yoshida M., Yukawa H., Hayashi K., Naitoh I., Miyabe K., Hori Y., Natsume M., Jinno N., Kato A., Kachi K., Asano G., Sahashi H., Toyohara Y., Kuno K., Kito Y., Kondo H., Hirano A., Okumura F., Anbe K., Baba Y., Kataoka H., Tanaka Y. Clinical impact of bile-derived exosomal miRNAs as novel diagnostic and prognostic biomarkers for biliary tract cancers, Cancer Sci. 2022; 114(1): 295-305.
  8. Tabata H., Sasaki M., Agetsuma M., Sano H., Hirota Y., Miyajima M., Hayashi K., Honda T., Nishikawa M., Inaguma Y., Ito H., Takebayashi H., Ema M., Ikenaka K., Nabekura J., Nagata K., Nakajima K. Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex, Nat. Commun. 2022; 13(1), 6571.
  9. Onoshima D., Hase T., Kihara N., Kuboyama D., Tanaka H., Ozawa N., Yukawa H., Sato M., Ishikawa K., Hasegawa Y., Ishii M., Hori M., Baba Y. Leukocyte depletion and size-based enrichment of circulating tumor cells using a pressure-sensing microfiltration device, ACS Meas. Sci. Au 2022; 3(2): 113-119.
  10. Nakase I., Miyai M., Noguchi K., Tamura M., Yamamoto Y., Nishimura Y., Omura M., Hayashi K., Futaki S., Tokonami S., Iida T. Light-Induced Condensation of Biofunctional Molecules around Targeted Living Cells to Accelerate Cytosolic Delivery, Nano Lett. 2022; 22(24): 9805-9814.

2021

  1. Nishimura Y., Oshimi K., Umehara Y., Kumon Y., Miyaji K., Yukawa H., Shikano Y., Matsubara T., Fujiwara M., Baba Y., Teki Y. Wide-field fluorescent nanodiamond spin measurements toward real-time large-area intracellular thermometry, Sci. Rep. 2021; 11(1): 4248.
  2. Yukawa H., Yamazaki S., Aoki K., Muto K., Kihara N., Sato K., Onoshima D., Ochiya T., Tanaka Y., Baba Y. Co-continuous structural effect of size-controlled macro-porous glass membrane on extracellular vesicle collection for the analysis of miRNA, Sci. Rep. 2021; 11(1): 8672.
  3. Rismaningsih N., Yamauchi H., Kameyama T., Yamamoto T., Morita S., Yukawa H., Uematsu T., Baba Y., Kuwabata S., Torimoto T. Photoluminescence properties of quinary Ag–(In,Ga)–(S,Se) quantum dots with a gradient alloy structure for in vivo bioimaging, J. Mater. Chem. C 2021; 9(34): 12791-12801.

2020

  1. Yukawa H., Fujiwara M., Kobayashi K., Miyaji K., Kumon Y., Nishimura Y., Oshimi K., Umehara Y., Teki Y., Iwasaki T., Hatano M., Hashimoto H., Baba Y. A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of the living stem cell function according to intracellular temperature, Nanoscale Adv. 2020; 2: 1859-1868. Inside Front Cover
  2. Nishinaga Y., Sato K., Yasui H., Taki S., Takahashi K., Shimizu M., Endo R., Koike C., Kuramoto N., Nakamura S., Fukui T., Yukawa H., Baba Y., Kaneko M. K., Chen-Yoshikawa T. F., Kobayashi H., Kato Y., Hasegawa Y. Targeted Phototherapy for Malignant Pleural Mesothelioma: Near-Infrared Photoimmunotherapy Targeting Podoplanin, Cells 2020; 9(4): E1019.
  3. Murata Y., Jo J., Yukawa H., Tsumaki N., Baba Y., Tabata Y. Visualization of Human Induced Pluripotent Stem Cells-Derived Three-Dimensional Cartilage Tissue by Gelatin Nanospheres, Tissue Eng. Part C Methods 2020; 26(5): 244-252.
  4. Fujiwara M., Sun S., Dohms A., Nishimura Y., Suto K., Takezawa Y., Oshimi K., Zhao L., Sadzak N., Umehara Y., Teki Y., Komatsu N., Benson O., Shikano Y., Kage-Nakadai E. Real-time nanodiamond thermometry probing in vivo thermogenic responses, Science Advances 2020; 6: 9636.
  5. Fujiwara M., Dohms A., Suto K., Nishimura Y., Oshimi K., Teki Y., Cai K., Benson O., Shikano Y. Real-time estimation of the optically detected magnetic resonance shift in diamond quantum thermometry toward biological applications, Phys. Rev. Research 2020; 2: 043415.
  6. Kameyama T., Yamauchi H., Yamamoto H., Mizumaki T., Yukawa H., Yamamoto M., Ikeda S., Uematsu T., Baba Y., Kuwabata S., Torimoto T. Tailored photoluminescence properties of Ag(In, Ga)Se2 quantum dots for near-infrared in vivo imaging, ACS Appl. Nano Mater. 2020; 3(4): 3275-3287. Front Cover
  7. Isobe Y., Sato K., Nishinaga Y., Takahashi K., Taki S., Yasui H., Shimizu M., Endo R., Koike C., Kuramoto N., Yukawa H., Nakamura S., Fukui T., Kawaguchi K., Chen-Yoshikawa T. F., Baba Y., Hasegawa Y. Near-infrared photoimmunotherapy targeting DLL3 for small cell lung cancer, eBioMedicine 2020; 52: 102632.
  8. Kitase Y., Sato Y., Ueda K., Suzuki T., Mikrogeorgiou A., Sugiyama Y., Matsubara K., Tsukagoshi Okabe Y., Shimizu S., Hirata H., Yukawa H., Baba Y., Tsuji M., Takahashi Y., Yamamoto A., Hayakawa M. A Novel Treatment with Stem Cells from Human Exfoliated Deciduous Teeth for Hypoxic-Ischemic Encephalopathy in Neonatal Rats, Stem Cells Dev. 2020; 29(2): 63-74. Front Cover
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